Imagine your daughter, your sister, your granddaughter living with the symptoms of autism, cerebral palsy, Parkinson’s, epilepsy, and scoliosis all at once. Imagine that she developed normally until she was 2 years old. She starts to walk, to say words, to explore the world around her. Then, suddenly, she stops. She loses the ability to balance, to use her hands and to speak. Imagine this bright, beautiful little girl that you love becomes trapped in a body that no longer cooperates. 350,000 girls and women live this tragedy, caused by a random genetic mutation.

This is Rett syndrome, and we need your help to cure it. That cure is not an "if", but a "when". Our beneficiary, the Rett Syndrome Research Trust, has made remarkable progress. Multiple clinical trials in gene therapy, all informed by RSRT-funded research, are underway and are showing early promising results. But we cannot rest for a moment. Your support now is more important than ever to build on this momentum and get us to a cure.

Thank you with all our hearts.